Structure of PDB 7mr3 Chain D Binding Site BS01

Receptor Information
>7mr3 Chain D (length=605) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHV
CLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMI
LCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEI
NWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRL
AAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQ
RLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQL
ASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDS
LCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSG
EDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGV
AGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIA
LDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAAL
ILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLA
ALFSS
Ligand information
Receptor-Ligand Complex Structure
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PDB7mr3 Heterogeneity in E. coli RecBCD Helicase-DNA Binding and Base Pair Melting.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		T205 T239 H241 A246 Q247 P248 E305 L444 R445 R486 N487 N495 T537 K540
Binding residue
(residue number reindexed from 1)		T204 T238 H240 A245 Q246 P247 E304 L443 R444 R485 N486 N494 T536 K539
Enzymatic activity
Enzyme Commision number 5.6.2.3: DNA 5'-3' helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005524 ATP binding
GO:0008854 exodeoxyribonuclease V activity
GO:0016853 isomerase activity
GO:0016887 ATP hydrolysis activity
GO:0017116 single-stranded DNA helicase activity
GO:0043139 5'-3' DNA helicase activity
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0000725 recombinational repair
GO:0006281 DNA repair
GO:0006302 double-strand break repair
GO:0006310 DNA recombination
GO:0006974 DNA damage response
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0009338 exodeoxyribonuclease V complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mr3, PDBe:7mr3, PDBj:7mr3
PDBsum7mr3
PubMed34246654
UniProtP04993|RECD_ECOLI RecBCD enzyme subunit RecD (Gene Name=recD)

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