Structure of PDB 7mj2 Chain D Binding Site BS01

Receptor Information

>7mj2 Chain D (length=205) Species: 220668 (Lactiplantibacillus plantarum WCFS1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NGFPEVIYGAGKTATQIVGIVQALSQQTLPILTTRLSAEKFAALQPALPT
AVYHATAQCMTVGEQPAPKTPGYIAVVTAGTSDQPVAEEAAVTAETFGNR
VERVYDVGVAGIHRLFAKLDVIRGARVVIVIAGMEGALASVVGGLVDKPV
IAVPTSVGYGTSFQGMTALLTMLNSCASGITVVNIDNGFGAAYSASMVNQ
MASWS

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

7mj2 Chain D Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7mj2 The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis.
Resolution	2.8 Å
Binding residue (original residue number in PDB)	S207 T212
Binding residue (residue number reindexed from 1)	S162 T167
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.5.1.143: pyridinium-3,5-biscarboxylic acid mononucleotide synthase.

Gene Ontology

	Molecular Function
GO:0016740	transferase activity
GO:0016787	hydrolase activity

	Biological Process
GO:0006189	'de novo' IMP biosynthetic process

	Cellular Component
GO:0005886	plasma membrane

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Cellular Component

External links

PDB	RCSB:7mj2, PDBe:7mj2, PDBj:7mj2
PDBsum	7mj2
PubMed	34548397
UniProt	F9UST0\|LARB_LACPL Pyridinium-3,5-biscarboxylic acid mononucleotide synthase (Gene Name=larB)

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