Structure of PDB 7lzi Chain D Binding Site BS01

Receptor Information
>7lzi Chain D (length=365) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGWVFPNNGKPLRIGVPNRVSYTDYVSKDKNPPGVRGYCIDVFEAAIELL
PYPVPRTYILYGDGKRNPSYDNLVNEVVADNFDVAVGDITIVTNRTRYVD
FTQPFIESGLVVVAPVKEAKSSPWSFLKPFTIEMWAVTGGFFLFVGAMVW
ILEQLITIFWFSFSTMSLGRFVLIIWLFVVLIINSSYTASLTSILTIRQL
TSRIEGIDSLVTSNEPIGVQDGTFARNYLINELNILPSRIVPLKDEEQYL
SALQRGPNAGGVAAIVDELPYIEVLLTNSNCKFRTVGQEFTRTGWGFAFQ
RDSPLAVDMSTAILQLSEEGELEKIHRKWLNYKHECSLSLKSFWGLFLIC
GITCFMALTVFFWRV
Ligand information
Ligand IDGLU
InChIInChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChIKeyWHUUTDBJXJRKMK-VKHMYHEASA-N
SMILES
SoftwareSMILES
ACDLabs 12.01O=C(O)C(N)CCC(=O)O
OpenEye OEToolkits 1.7.0C(CC(=O)O)C(C(=O)O)N
OpenEye OEToolkits 1.7.0C(CC(=O)O)[C@@H](C(=O)O)N
CACTVS 3.370N[C@@H](CCC(O)=O)C(O)=O
CACTVS 3.370N[CH](CCC(O)=O)C(O)=O
FormulaC5 H9 N O4
NameGLUTAMIC ACID
ChEMBLCHEMBL575060
DrugBankDB00142
ZINCZINC000001482113
PDB chain7lzi Chain D Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7lzi Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4.
Resolution4.39 Å
Binding residue
(original residue number in PDB)		Y552 D570 T572 R577 Q725 G727 T728 F729 E773 Y776
Binding residue
(residue number reindexed from 1)		Y70 D88 T90 R95 Q220 G222 T223 F224 E268 Y271
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:7lzi, PDBe:7lzi, PDBj:7lzi
PDBsum7lzi
PubMed34161757
UniProtQ8GXJ4|GLR34_ARATH Glutamate receptor 3.4 (Gene Name=GLR3.4)

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