Structure of PDB 7kzd Chain D Binding Site BS01

Receptor Information
>7kzd Chain D (length=438) Species: 1396 (Bacillus cereus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTTISGHSKDNLALLKCLQGETKEKEFEISNVLPNHKMKEKLFRENKLKI
DIDIEKDIFNYSRKNIQKIEFMPVNRLISQSEIDGIIGTLKEVLPTGQFT
SGPFSKKLEEVIGDYLNKKYVIATSSGTDALMVSLLSIGIQPGDEVIMPA
NSFAATENAVLAIGAKPVFVDIDHKSYCIDPLKIEEAITQKTKCILPVHL
YGKQCDMKRIREIADVYQLRIIEDACQAIGSSNLGEYGDIIILSFNPYKN
FGVCGKAGAIVTNNENLAIRCNQYSYHGFEVDKKNKKVLDFGFNSKIDNL
QAAIGLERIKFLSYNNLKRVFLAQRYIRNLKELEDRELIKLPRMTEDNVW
HLFPIRIINGRRDEVKNKLYQLYNIETDIYYPVLSHKHNTKLVKKNYMQD
TLLNTEQVHKEILHLPLHPNMLLEEQNFVLEGLINVNK
Ligand information
Ligand IDGUA
InChIInChI=1S/C5H8O4/c6-4(7)2-1-3-5(8)9/h1-3H2,(H,6,7)(H,8,9)
InChIKeyJFCQEDHGNNZCLN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CC(=O)O)CC(=O)O
ACDLabs 10.04O=C(O)CCCC(=O)O
CACTVS 3.341OC(=O)CCCC(O)=O
FormulaC5 H8 O4
NameGLUTARIC ACID
ChEMBLCHEMBL1162495
DrugBankDB03553
ZINCZINC000000388706
PDB chain7kzd Chain D Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7kzd Snapshots along the catalytic path of KabA, a PLP-dependent aminotransferase required for kanosamine biosynthesis in Bacillus cereus UW85.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		Y253 K254 H356
Binding residue
(residue number reindexed from 1)		Y248 K249 H351
Annotation score2
Enzymatic activity
Enzyme Commision number 2.6.1.1: aspartate transaminase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0000271 polysaccharide biosynthetic process

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:7kzd, PDBe:7kzd, PDBj:7kzd
PDBsum7kzd
PubMed33984505
UniProtC0JRF5

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