Structure of PDB 7ktx Chain D Binding Site BS01

Receptor Information
>7ktx Chain D (length=74) Species: 1266529 (Saccharomyces cerevisiae BY4743) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EWAKHLLDTKYIEKYNIQNSNTLPMFMYIVFQGVLMYIGYRKLNSMGLIP
NAKGDWLPWERIAHYNNGLQWFSD
Ligand information
>7ktx Chain N (length=24) Species: 1266529 (Saccharomyces cerevisiae BY4743) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB7ktx Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.
Resolution4.3 Å
Binding residue
(original residue number in PDB)		Y144 F147 I154 K158
Binding residue
(residue number reindexed from 1)		Y28 F31 I38 K42
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0032977 membrane insertase activity
Biological Process
GO:0006644 phospholipid metabolic process
GO:0015914 phospholipid transport
GO:0034975 protein folding in endoplasmic reticulum
GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0072546 EMC complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ktx, PDBe:7ktx, PDBj:7ktx
PDBsum7ktx
PubMed33236988
UniProtP53073|EMC4_YEAST ER membrane protein complex subunit 4 (Gene Name=EMC4)

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