Structure of PDB 7kd7 Chain D Binding Site BS01

Receptor Information
>7kd7 Chain D (length=202) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNGLNVSIECKRVSGLE
PATVDWAFDLTKTNMQTMYEQSEWGWKDREKREEMTDDRAWYLIAWENSS
VPVAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQILQLMANST
QMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSR
RT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7kd7 Novel Bisubstrate Inhibitors for Protein N-Terminal Acetyltransferase D.
Resolution1.44 Å
Binding residue
(original residue number in PDB)		Y85 W90 D127 E129 Y136 Y138 E139 T174 P199 Y211 I213
Binding residue
(residue number reindexed from 1)		Y69 W74 D111 E113 Y120 Y122 E123 T158 P183 Y195 I197
Enzymatic activity
Enzyme Commision number 2.3.1.257: N-terminal L-serine N(alpha)-acetyltransferase NatD.
Gene Ontology
Molecular Function
GO:0010485 histone H4 acetyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0043998 histone H2A acetyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7kd7, PDBe:7kd7, PDBj:7kd7
PDBsum7kd7
PubMed34110812
UniProtQ86UY6|NAA40_HUMAN N-alpha-acetyltransferase 40 (Gene Name=NAA40)

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