Structure of PDB 7jk5 Chain D Binding Site BS01

Receptor Information
>7jk5 Chain D (length=441) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PEADRELVSIRRFLKERLQRDYTTLRGYAKERSNVRLLLQRTAEMGESNS
LLLLGPRGSGKTTLINSVLADLLPNKSFGENTLIVHLDGNLHTDDRVALK
SITVQMQLENAADGKVFGSFAENLAFLLQCLKAGGKHSKSVIFILEEFDL
FCAHHNQTLLYNLFDVSQSAQAPICVLGVTCRLDVIELLEKRVKSRFSHR
QVFLFPSLRRFEDYVDLCRDLLSLPTGNSLLLAAEKIYNLQNIYFSRNHF
DPGEYGFSPRLRDAWNKQICKVLATQQARSTLQALHDFDISEAYLKNFLF
RLVAHLRPQSPHITAEKMAAVGSQFEGDDKIELLCGLSVLELCLIIAIKH
HSQIYDRDSFNFEIIYARFSKFAKVSTTMQAVERSIVLKAFEHLRIAELI
MPLTVQKEFEMHKLALTYSQIHHCMQRYQALPTEVAQWAQS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7jk5 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Resolution3.9 Å
Binding residue
(original residue number in PDB)
R97 S120
Binding residue
(residue number reindexed from 1)
R96 S119
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
GO:0016887 ATP hydrolysis activity
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
Cellular Component
GO:0000808 origin recognition complex
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005664 nuclear origin of replication recognition complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7jk5, PDBe:7jk5, PDBj:7jk5
PDBsum7jk5
PubMed32848132
UniProtQ9W102

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