Structure of PDB 7f7i Chain D Binding Site BS01
Receptor Information
>7f7i Chain D (length=182) Species:
10116
(Rattus norvegicus) [
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HYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYH
FVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVS
ANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLE
QEFTECFSAIVEGDSFEEIYHKVKRVIEDLSG
Ligand information
>7f7i Chain G (length=12) Species:
32630
(synthetic construct) [
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RIRRDEYLKAIQ
Receptor-Ligand Complex Structure
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PDB
7f7i
Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain.
Resolution
2.595 Å
Binding residue
(original residue number in PDB)
H532 Y533 H642 H644 L711 G713
Binding residue
(residue number reindexed from 1)
H1 Y2 H111 H113 L180 G182
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7f7i
,
PDBe:7f7i
,
PDBj:7f7i
PDBsum
7f7i
PubMed
34458841
UniProt
P31016
|DLG4_RAT Disks large homolog 4 (Gene Name=Dlg4)
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