Structure of PDB 7f0r Chain D Binding Site BS01

Receptor Information
>7f0r Chain D (length=1339) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFDAIRIGLASPEMIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPV
KDYECLCGKYKRLKHRGVICEKCGVEVALAKVRRERMGHIELASPVAHIW
FLKSLPSRIGLLLDMTLRDIERVLYFESYVVIDPGMTTLEKGQLLNDEQY
FEALEEFGDDFDARMGAEAVHELLNAIDLEHEIGRLREEIPQTNSETKIK
KLSKRLKLMEAFQGSGNKPEWMVLTVLPVLPPDLRPLVPLDGGRFATSDL
NDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRA
ITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQ
CGLPKKMALELFKPFIFGKLEGRGMATTIKAAKKMVERELPEVWDVLAEV
IREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQ
MAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVMGLYYMTR
EAINAKGEGMAFADLQEVDRAYRSGQASLHARVKVRINEKIKGEDGQLTA
NTRIVDTTVGRALLFQVVPAGLPFDVVNQSMKKKAISKLINHCYRVVGLK
DTVIFADQLMYTGFAYSTISGVSIGVNDFVIPDEKARIINAATDEVKEIE
SQYASGLVTQGEKYNKVIDLWSKANDEVSKAMMANLSKEKVVDREGKEVD
QESFNSMYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFRE
GLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEIDCG
TEHGLLMSPHIEGGDVVEPLGERVLGRVIARDVFKPGSDEVIVPAGTLID
EKWVDFLEVMSVDEVVVRSPITCETRHGICAMCYGRDLARGHRVNIGEAV
GVIAAQSIGEPGTQLTAADNVQVKNGGTIRLHNLKHVVRADGALVAVSRS
GELAVADDFGRERERYKLPYGAVISVKEGDKVDPGAIVAKWDPHTHPIVT
EVDGTVAFVGMEEGITVKRQTDELTGLTNIEVMDPKDRPAAGKDIRPAVK
LIDAAGKDLLLPGTDVPAQYFLPANALVNLTDGAKVSIGDVVARIPQTGG
LPRVADLFEARRPKEPSILAEISGTISFGKETKGKRRLVITPNDGSDPYE
ELIPKWRHLNVFEGEQVNRGEVISDGPSNPHDILRLLGVSSLAKYIVNEI
QDVYRLQGVKINDKHIETILRQMLRKVEVSESGDSSFIKGDQVELTQVLE
ENEQLGTEDKFPAKYERVLLGITKASLSTESFISAASFQETTRVLTEAAV
TGKRDFLRGLKENVVVGRLIPAGTGLAYHSERKRQRDLG
Ligand information
Receptor-Ligand Complex Structure
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PDB7f0r Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding.
Resolution5.8 Å
Binding residue
(original residue number in PDB)
T208 N209 S210 E211 E1327
Binding residue
(residue number reindexed from 1)
T193 N194 S195 E196 E1290
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7f0r, PDBe:7f0r, PDBj:7f0r
PDBsum7f0r
PubMed35859063
UniProtQ9HWC9|RPOC_PSEAE DNA-directed RNA polymerase subunit beta' (Gene Name=rpoC)

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