Structure of PDB 7eyw Chain D Binding Site BS01

Receptor Information
>7eyw Chain D (length=252) Species: 5065 (Aspergillus sp.) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQLHYVPYDTPVEDVMRILKESGTLVIRNFLDQNTVQKVQDEVDPSNLSL
MSKTYRCEVLNHPWMHAICERMFGPTYGDYWFNGGAILHLEPGENTQPIH
QDHVFYQISKWRRPTDPDLTINFTMALTEFTVENGGTRVCPGSHLWENGH
ASPAEEDMVPVLMQPGDALILPGSMWHSAGANRTSEYRRGFATSFHPCHF
TPIESHHHLPREMVEEMTPLVQKMLGFRTLNLHNNVKVWKAGEGNLEDAT
GL
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain7eyw Chain D Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7eyw Molecular insights into the unusually promiscuous and catalytically versatile Fe(II)/ alpha-ketoglutarate-dependent oxygenase SptF.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		H128 D130 H205
Binding residue
(residue number reindexed from 1)		H100 D102 H177
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity

View graph for
Molecular Function
External links
PDB RCSB:7eyw, PDBe:7eyw, PDBj:7eyw
PDBsum7eyw
PubMed35013177
UniProtA0A6J4CX17

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