Structure of PDB 7d7e Chain D Binding Site BS01

Receptor Information
>7d7e Chain D (length=471) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELYVKTTLRELVVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSD
SGVSFQTISSMSDFWDFAQGPLLDSLYWTKGSHSFIYYENLLLGAPRLRQ
LRVRNDSCVVHEDFREDILNCYDVYSPDKEDQLPFGPQNGTAWTYHSQNE
LGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQGLQEGLWLDRGTRVVF
IDFSVYNANINLFCILRLVVEFPATGGTIPSWQIRTVKLIRYVNNWDFFI
VGCEVVFCVFIFYYVVEEILEIHLHRLRYLSSVWNILDLVVILLSIVAVG
FHIFRTLEVNRLMGKLLQQPDTYADFEFLAFWQTQYNNMNAVNLFFAWIK
IFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQ
VENFSTFVKCIFTQFRIILGDFDYNAIDNANRILGPVYFVTYVFFVFFVL
LNMFLAIINDTYSEVKEELAG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7d7e Chain D Residue 803 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7d7e Structural basis for Ca 2+ activation of the heteromeric PKD1L3/PKD2L1 channel.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		E370 E373 N387 D390
Binding residue
(residue number reindexed from 1)		E268 E271 N285 D288
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:7d7e, PDBe:7d7e, PDBj:7d7e
PDBsum7d7e
PubMed34381056
UniProtA2A259|PK2L1_MOUSE Polycystin-2-like protein 1 (Gene Name=Pkd2l1)

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