Structure of PDB 7cx7 Chain D Binding Site BS01

Receptor Information
>7cx7 Chain D (length=494) Species: 235909,1202714 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSLRPYEFWFVTGSQHLGEEALKQVEEHSRIMVNEWNRDSVFPFPFVFKS
VVTTPEEIRRVCLEANASEQCAGVVTWMHTFSPAKMWIGGLLELRKPLLH
LHTQFNRDIPWDSIDMDFMNLNQSAHGDREFGFMVTRLGMPRKVIVGHWQ
DAEVARRVRGWAMTAVAAAVSRGLKVARFGDNMRQVAVTEGDKVEAEARF
GWSVNGYGVGDLAERVRAVSEAEIDRLIDEYQSLYEFAPGCEKGGPLHDG
VREQARIELGLRSFLEEGGFEAFTTTFEDLHGMKQLPGLAVQRLMAEGYG
FGGEGDWKTAALVRLMKVMADGKGTSFMEDYTYHFEPGNEMILGAHMLEV
CPTIAATRPRIEVHPLSIGGKEDPARLVFDGGEGAAVNASLIDLGHRFRL
IVNEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSF
AVTTEQLQDFAEMAGIECVVINEHTSVSSFKNELKWNEVFWRGR
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7cx7 Chain D Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7cx7 Crystal structure of Arabinose isomerase from hyper thermophilic bacterium Thermotoga maritima (TMAI) wt
Resolution2.49 Å
Binding residue
(original residue number in PDB)		E307 E332 H349 H447 H448
Binding residue
(residue number reindexed from 1)		E304 E329 H346 H444 H445
Annotation score1
Enzymatic activity
Enzyme Commision number 5.3.1.4: L-arabinose isomerase.
Gene Ontology
Molecular Function
GO:0008733 L-arabinose isomerase activity
GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses
Biological Process
GO:0005996 monosaccharide metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7cx7, PDBe:7cx7, PDBj:7cx7
PDBsum7cx7
PubMed
UniProtK0IGW6;
Q5KYP7|ARAA_GEOKA L-arabinose isomerase (Gene Name=araA)

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