Structure of PDB 7cux Chain D Binding Site BS01

Receptor Information

>7cux Chain D (length=295) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKAEI
ENKGYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNTEAGVPLAT
LCSNLYHRERTSTDVMDSQEALAFLKCRTQNVSAAALFDRKRLQYLEKLN
LPESTHVEFVMFSTDVSHCVKDRLPKCVSAFANTEGGYVFFGVHDETCQV
IGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGA
LRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMM

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

7cux Chain D Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	7cux Crystal structure of human Schlafen 5 N'-terminal domain (SLFN5-N) involved in ssRNA cleaving and DNA binding
Resolution	3.29477 Å
Binding residue (original residue number in PDB)	H266 C302 C303
Binding residue (residue number reindexed from 1)	H228 C264 C265
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:7cux, PDBe:7cux, PDBj:7cux
PDBsum	7cux
PubMed
UniProt	Q08AF3\|SLFN5_HUMAN Schlafen family member 5 (Gene Name=SLFN5)

[Back to BioLiP]