Structure of PDB 7ccq Chain D Binding Site BS01

Receptor Information
>7ccq Chain D (length=92) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTS
Ligand information
>7ccq Chain I (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acaggatgtatatatctgacacgtgcctggagactagggagtaatcccct
tggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgcta
gagctgtctacgaccaattgagcggcctcggcaccgggattctccag
Receptor-Ligand Complex Structure
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PDB7ccq Structural basis for nucleosome-mediated inhibition of cGAS activity.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		Y42 I54 S55 S56 R86 S87 T88
Binding residue
(residue number reindexed from 1)		Y11 I23 S24 S25 R55 S56 T57
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:7ccq, PDBe:7ccq, PDBj:7ccq
PDBsum7ccq
PubMed33051594
UniProtP06899|H2B1J_HUMAN Histone H2B type 1-J (Gene Name=H2BC11)

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