Structure of PDB 7c7a Chain D Binding Site BS01

Receptor Information
>7c7a Chain D (length=251) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DRTQTFIKDCLFTKCLEDPEKPFNENRFQDTLLLLPTDESADKQLEKRDY
QRINKNSKIALREYINNCKKNTKKCLKLAYENKITDKEDLLHYIEEKHPT
IYESLPQYVDFVPMYKELWINYIKELLNITKNLKTFNGSLALLKLSMADY
NGALLRVTKSKNKTLIGLQGIVIWDSQKFFIMIVKGNIIDEIKCIPKKGT
VFQFEIPISDDDDSALRYSILGDRFKYRSVDRAGRKFKSRRCDDMLYYIQ
N
Ligand information
>7c7a Chain A (length=330) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauccaugaccaaagaaucgucacaaaucgaagcuuacaaaauggaguaa
aauuuuguuuacucaguaauaugcuuuggguugaaagucucccaccaauu
cguaugcggaaaacguaaugagauuuaaaaaaauuguuuaaaucaacuca
uuaaggaggaugcccuuggguauucugcuucuugaccugguaccucuauu
gcaggguacugguguuuucuucgguacuggauuccguuuguauggaaucu
aaaccauaguuaugacgauugcucuuucccgugcuggaucgaguaaccca
auggagcuuacuauucuugguccauggauu
<<<<<<<<<<<<<<.<<<<<<<......<<<<<<..........<<<<<<
<......>>>>>>>........>>>>>>........[.((((.<<<....
.....<<<.....>>><<<<<..........................>>>
>><<<.<<<<<<<<....>>>>>>>>.>>>......<<<<<<<<<.....
...>>>>>>>>>..........>>>...<<<<<<<<......>>>>>>>>
.............>>>>>>><<<<..<<<......>>>..>>>>......
..)))).]...>....>>>>>>.>>>>>>>
Receptor-Ligand Complex Structure
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PDB7c7a Structural insight into precursor ribosomal RNA processing by ribonuclease MRP.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		T38 K75 Y78 Q79 K86 R90 N94 K97 K101 K105 N190 T192 W202 K221 Y255 K266 R268 R269
Binding residue
(residue number reindexed from 1)		T37 K47 Y50 Q51 K58 R62 N66 K69 K73 K77 N162 T164 W174 K193 Y227 K238 R240 R241
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000171 ribonuclease MRP activity
GO:0003723 RNA binding
GO:0004526 ribonuclease P activity
GO:0005515 protein binding
GO:0033204 ribonuclease P RNA binding
GO:0042134 rRNA primary transcript binding
Biological Process
GO:0000294 nuclear-transcribed mRNA catabolic process, RNase MRP-dependent
GO:0000460 maturation of 5.8S rRNA
GO:0001682 tRNA 5'-leader removal
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0008033 tRNA processing
GO:0034965 intronic box C/D snoRNA processing
Cellular Component
GO:0000172 ribonuclease MRP complex
GO:0005634 nucleus
GO:0005655 nucleolar ribonuclease P complex
GO:0030677 ribonuclease P complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7c7a, PDBe:7c7a, PDBj:7c7a
PDBsum7c7a
PubMed32586950
UniProtP38336|POP4_YEAST RNases MRP/P 32.9 kDa subunit (Gene Name=POP4)

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