Structure of PDB 7bwu Chain D Binding Site BS01

Receptor Information
>7bwu Chain D (length=447) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GCGAPVHDPDYIGGIGKELIVDDISDVTSFYPSAYQEHLNFIPAPTTGSG
CTRIPSFDMSTTHYCYTHNVILSGCRDHSHSHQYLALGVLRTSATGRVFF
STLRSINLDDTQNRKSCSVSATPLGCDMLCSKVTETEEEDYKSVAPTSMV
HGRLGFDGQYHEKDLDTTVLFKDWVANYPGVGGGSFIDDRVWFPVYGGLK
PNSPSDTAQEGKYVIYKRHNNTCPDEQDYQIRMAKSSYKPGRFGGKRVQQ
AILSIKVSTSLGKDPVLTIPPNTITLMGAEGRILTVGTSHFLYQRGSSYF
SPALLYPMTVNNKTATLHSPYTFNAFTRPGSVPCQASARCPNSCITGVYT
DPYPLIFHRNHTLRGVFGTMLDDEQARLNPVSAVFDNISRSRVTRVSSSS
TKAAYTTSTCFKVVKTNKAYCLSIAEISNTLFGEFRIVPLLVEILKD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7bwu Chain D Residue 1203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7bwu Restructuring a dimer antigen in transgenic rice system for high efficient B cell activation: Development of a super effective vaccine against Newcastle Disease Virus
Resolution1.87 Å
Binding residue
(original residue number in PDB)		D261 S264 A266 V296
Binding residue
(residue number reindexed from 1)		D140 S143 A145 V175
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
GO:0016787 hydrolase activity
GO:0046789 host cell surface receptor binding
GO:0046872 metal ion binding
Biological Process
GO:0019058 viral life cycle
GO:0019062 virion attachment to host cell
GO:0046718 symbiont entry into host cell
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0019031 viral envelope
GO:0020002 host cell plasma membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7bwu, PDBe:7bwu, PDBj:7bwu
PDBsum7bwu
PubMed
UniProtI7EFR1

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