Structure of PDB 7b03 Chain D Binding Site BS01

Receptor Information
>7b03 Chain D (length=217) Species: 86473 (uncultured Gammaproteobacteria bacterium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DASDYTGVSFWLVTAALLASTVFFFVERDRVSAKWKTSLTVSGLVTGIAF
WHYMYMRGVWIETGDSPTVFRYIDWLLTVPLLICEFYLILAAATNVAGSL
FKKLLVGSLVMLVFGYMGEAGIMAAWPAFIIGCLAWVYMIYELWAGEGKS
ACNTASPAVQSAYNTMMYIIIFGWAIYPVGYFTGYLNLNLIYNLADFVNK
ILFGLIIWNVAVKESSN
Ligand information
Ligand IDRET
InChIInChI=1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
InChIKeyNCYCYZXNIZJOKI-OVSJKPMPSA-N
SMILES
SoftwareSMILES
CACTVS 3.370CC(=C\C=O)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C
ACDLabs 12.01O=C\C=C(\C=C\C=C(\C=C\C1=C(C)CCCC1(C)C)C)C
OpenEye OEToolkits 1.7.0CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C=O)/C)/C
OpenEye OEToolkits 1.7.0CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=O)C)C
CACTVS 3.370CC(=CC=O)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
FormulaC20 H28 O
NameRETINAL
ChEMBLCHEMBL81379
DrugBank
ZINCZINC000004228262
PDB chain7b03 Chain D Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7b03 Cryo-EM structure and dynamics of the green-light absorbing proteorhodopsin
Resolution2.93 Å
Binding residue
(original residue number in PDB)		W99 V103 M135 W198 Y201 P202 K232
Binding residue
(residue number reindexed from 1)		W75 V79 M111 W174 Y177 P178 K200
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0009881 photoreceptor activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0007602 phototransduction
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7b03, PDBe:7b03, PDBj:7b03
PDBsum7b03
PubMed
UniProtQ6J4G7|PRRG_UNKP Green-light absorbing proteorhodopsin

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