Structure of PDB 7azf Chain D Binding Site BS01
Receptor Information
>7azf Chain D (length=368) Species:
1444266
(Escherichia coli 2-427-07_S4_C3) [
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SHMKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTD
LEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERML
VRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAH
QDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRK
GVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVL
PKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPE
QEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQ
IEDAASQSAAYVVMPMRL
Ligand information
>7azf Chain H (length=6) Species:
32630
(synthetic construct) [
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tQFDLF
Receptor-Ligand Complex Structure
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PDB
7azf
Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
Resolution
1.93 Å
Binding residue
(original residue number in PDB)
Y153 Y154
Binding residue
(residue number reindexed from 1)
Y155 Y156
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003887
DNA-directed DNA polymerase activity
GO:0005515
protein binding
GO:0008408
3'-5' exonuclease activity
GO:0042802
identical protein binding
GO:0042803
protein homodimerization activity
Biological Process
GO:0006260
DNA replication
GO:0006261
DNA-templated DNA replication
GO:0006271
DNA strand elongation involved in DNA replication
GO:0006974
DNA damage response
GO:0030174
regulation of DNA-templated DNA replication initiation
GO:0032297
negative regulation of DNA-templated DNA replication initiation
GO:0042276
error-prone translesion synthesis
GO:0044787
bacterial-type DNA replication
Cellular Component
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0009360
DNA polymerase III complex
GO:0030894
replisome
GO:1990078
replication inhibiting complex
GO:1990085
Hda-beta clamp complex
View graph for
Molecular Function
View graph for
Biological Process
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Cellular Component
External links
PDB
RCSB:7azf
,
PDBe:7azf
,
PDBj:7azf
PDBsum
7azf
PubMed
34806883
UniProt
P0A988
|DPO3B_ECOLI Beta sliding clamp (Gene Name=dnaN)
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