Structure of PDB 6zvg Chain D Binding Site BS01

Receptor Information
>6zvg Chain D (length=388) Species: 408968 (Psychrobacter sp. B6) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPILGLVEKFAADNNPDKVNLGIGIYYDESGVMPVLDCVKIAEQRIADPI
SPRPYLPMAGLPGHRKGCQELLFGKDAPVLKDGLVATIATIGGSGALKVG
AEFIHEWFPQSKCYVSDPTWGNHIAIFEGCDIEVGKYPYYDTATGGIKFD
EMIAFFETLNKDDVLLLHPCCHNPTGVDLTREQWDTVLNVIQERELIPFM
DIAYQGFGEDMDSDAYAIRKAVDMGLPLFVSNSFSKNLSLYGERVGGLSV
VCPTVDETERVFGQLNSTVRRIYSSPPSHGGRVVDIVMNDAALHEQWVGE
VYAMRDRIKSMRTKLKSVLEAKISGRNFDYLTAQNGMFSFTGLTPEQVER
LQSEFGIYMISNSRMCVAGLNSSNIDYVANAMVDVLKD
Ligand information
Ligand ID3IL
InChIInChI=1S/C11H11NO3/c13-10(11(14)15)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,10,12-13H,5H2,(H,14,15)/t10-/m0/s1
InChIKeyXGILAAMKEQUXLS-JTQLQIEISA-N
SMILES
SoftwareSMILES
CACTVS 3.341O[CH](Cc1c[nH]c2ccccc12)C(O)=O
OpenEye OEToolkits 1.5.0c1ccc2c(c1)c(c[nH]2)C[C@@H](C(=O)O)O
CACTVS 3.341O[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
OpenEye OEToolkits 1.5.0c1ccc2c(c1)c(c[nH]2)CC(C(=O)O)O
ACDLabs 10.04O=C(O)C(O)Cc2c1ccccc1nc2
FormulaC11 H11 N O3
Name3-(INDOL-3-YL) LACTATE;
(2S)-2-HYDROXY-3-(1H-INDOL-3-YL)PROPANOIC ACID
ChEMBL
DrugBankDB07060
ZINCZINC000000039098
PDB chain6zvg Chain C Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6zvg Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from Psychrobacter Sp. B6.
Resolution2.59 Å
Binding residue
(original residue number in PDB)		Y65 S284
Binding residue
(residue number reindexed from 1)		Y55 S274
Annotation score1
Enzymatic activity
Enzyme Commision number 2.6.1.-
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004838 L-tyrosine-2-oxoglutarate transaminase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006520 amino acid metabolic process
GO:0009058 biosynthetic process
GO:0033585 L-phenylalanine biosynthetic process from chorismate via phenylpyruvate
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zvg, PDBe:6zvg, PDBj:6zvg
PDBsum6zvg
PubMed34204354
UniProtC7E5X4

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