Structure of PDB 6zr5 Chain D Binding Site BS01

Receptor Information
>6zr5 Chain D (length=38) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YSDDKPFLCTAPGCGRRFTNEDHLAVHKRKHEMTLKFG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6zr5 Chain D Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zr5 Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38.
Resolution2.699 Å
Binding residue
(original residue number in PDB)		C27 C32 H45 H49
Binding residue
(residue number reindexed from 1)		C9 C14 H27 H31
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
External links
PDB RCSB:6zr5, PDBe:6zr5, PDBj:6zr5
PDBsum6zr5
PubMed33188182
UniProtP15336|ATF2_HUMAN Cyclic AMP-dependent transcription factor ATF-2 (Gene Name=ATF2)

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