Structure of PDB 6zlz Chain D Binding Site BS01

Receptor Information

>6zlz Chain D (length=346) Species: 493803 (Merkel cell polyomavirus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

IPKPGCCPNVASVPKLLVKGGVEVLSVVTGEDSITQIELYLNPRMGVNSP
DLPTTSNWYTYTYDLQPKGSSPDQPIKENLPAYSVARVSLPMLNEDITCD
TLQMWEAISVKTEVVGISSLINVHYWDMKRVHDYGAGIPVSGVNYHMFAI
GGEPLDLQGLVLDYQTQYPKTTNGGPITIETVLGRKMTPKNQGLDPQAKA
KLDKDGNYPIEVWCPDPSKNENSRYYGSIQTGSQTPTVLQFSNTLTTVLL
DENGVGPLCKGDGLFISCADIVGFLFKTSGKMALHGLPRYFNVTLRKRWV
KNPYPVVNLINSLFSNLMPKVSGQPMEGKDNQVEEVRIYEGSEQLP

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

6zlz Chain C Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6zlz Structure of Merkel Cell Polyomavirus Capsid and Interaction with Its Glycosaminoglycan Attachment Receptor.
Resolution	3.52 Å
Binding residue (original residue number in PDB)	S236 E239
Binding residue (residue number reindexed from 1)	S218 E221
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005198	structural molecule activity
GO:0046872	metal ion binding

	Cellular Component
GO:0019028	viral capsid
GO:0042025	host cell nucleus
GO:0044423	virion component

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Molecular Function

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Cellular Component

External links

PDB	RCSB:6zlz, PDBe:6zlz, PDBj:6zlz
PDBsum	6zlz
PubMed	32699083
UniProt	B0G0W3

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