Structure of PDB 6xwh Chain D Binding Site BS01

Receptor Information
>6xwh Chain D (length=78) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDK
RQRNRCQYCRYQKCLAMGMKREAVQEER
Ligand information
Receptor-Ligand Complex Structure
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PDB6xwh Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		H146 Y147 R164 Q206
Binding residue
(residue number reindexed from 1)		H15 Y16 R33 Q75
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6xwh, PDBe:6xwh, PDBj:6xwh
PDBsum6xwh
PubMed32974652
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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