Structure of PDB 6xb8 Chain D Binding Site BS01

Receptor Information
>6xb8 Chain D (length=196) Species: 648242 (Adeno-associated virus 2 Srivastava/1982) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPGFYEIVIKVPSDLDEHLPGISDSFVNWVAEKEWELPPDSDMDLNLIEQ
APLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGV
KSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDE
SYIPNYLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6xb8 The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.
Resolution3.3 Å
Binding residue
(original residue number in PDB)
F26 W29 E57 K58 R61 I120 R122
Binding residue
(residue number reindexed from 1)
F26 W29 E57 K58 R61 I120 R122
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
External links
PDB RCSB:6xb8, PDBe:6xb8, PDBj:6xb8
PDBsum6xb8
PubMed33270897
UniProtP03132|REP68_AAV2S Protein Rep68 (Gene Name=Rep68)

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