Structure of PDB 6x8k Chain D Binding Site BS01

Receptor Information
>6x8k Chain D (length=92) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMH
ILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY
Ligand information
Receptor-Ligand Complex Structure
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PDB6x8k Caspase-3 in complex with elongated ketomethylene inhibitor
Resolution2.17 Å
Binding residue
(original residue number in PDB)		Y204 S205 W206 R207 N208 S209 S249
Binding residue
(residue number reindexed from 1)		Y20 S21 W22 R23 N24 S25 S65
Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6x8k, PDBe:6x8k, PDBj:6x8k
PDBsum6x8k
PubMed
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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