Structure of PDB 6x8j Chain D Binding Site BS01

Receptor Information
>6x8j Chain D (length=91) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQI
LTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFS
Ligand information
Receptor-Ligand Complex Structure
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PDB6x8j Caspase-7 in complex with ketomethylene inhibitor reveals tetrahedral adduct
Resolution2.604 Å
Binding residue
(original residue number in PDB)		Y230 S231 W232 R233 S234 P235 Q276
Binding residue
(residue number reindexed from 1)		Y19 S20 W21 R22 S23 P24 Q65
Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6x8j, PDBe:6x8j, PDBj:6x8j
PDBsum6x8j
PubMed
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

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