Structure of PDB 6x0n Chain D Binding Site BS01
Receptor Information
>6x0n Chain D (length=98) Species:
8355
(Xenopus laevis) [
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KRRKTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEA
SRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Ligand information
>6x0n Chain I (length=157) [
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caatacatgcacaggatgtatatatctgacacgtgcctggagactaggga
gtaatccccttggcggttaaaacgcgggggacagcgcgtacgtgcgttta
agcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggat
tctccag
Receptor-Ligand Complex Structure
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PDB
6x0n
Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Resolution
10.0 Å
Binding residue
(original residue number in PDB)
R26 R27 R30 E32 Y39 S52 S53 S84
Binding residue
(residue number reindexed from 1)
R2 R3 R6 E8 Y15 S28 S29 S60
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0005515
protein binding
GO:0030527
structural constituent of chromatin
GO:0046982
protein heterodimerization activity
Cellular Component
GO:0000786
nucleosome
GO:0005634
nucleus
GO:0005694
chromosome
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Molecular Function
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Cellular Component
External links
PDB
RCSB:6x0n
,
PDBe:6x0n
,
PDBj:6x0n
PDBsum
6x0n
PubMed
32939087
UniProt
P02281
|H2B11_XENLA Histone H2B 1.1
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