Structure of PDB 6wz9 Chain D Binding Site BS01

Receptor Information
>6wz9 Chain D (length=92) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTS
Ligand information
>6wz9 Chain I (length=148) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cacaggatgtatatatctgacacgtgcctggagactagggagtaatcccc
ttggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgct
agagctgtctacgaccaattgagcggcctcggcaccgggattctccag
Receptor-Ligand Complex Structure
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PDB6wz9 Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		T29 Y39 S52 S53 R83 S84 T85
Binding residue
(residue number reindexed from 1)		T1 Y11 S24 S25 R55 S56 T57
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6wz9, PDBe:6wz9, PDBj:6wz9
PDBsum6wz9
PubMed32939087
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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