Structure of PDB 6wqn Chain D Binding Site BS01

Receptor Information
>6wqn Chain D (length=100) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLFVGGDSVKVGA
PTVEGATVTATVNKQGRGKKITVFTYKRRKNSKRKKGHRQPYTKLTIDKI
Ligand information
>6wqn Chain 1 (length=2687) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaguuauuaagggcgcacgguggaugccuuggcacuagaagccgaugaa
ggacguuacuaacgacgauaugcuuuggggagcuguaaguaagcuuugau
ccagagauuuccgaauggggaaacccagcaugaguuaugucauguuaucg
auaugugaauacauagcauaucagaaggcacacccggagaacugaaacau
cuuaguacccggaggaagagaaagaaaauucgauucccuuaguagcggcg
agcgaaacgggaagagcccaaaccaacguugggguuguaggacacucuag
uuacaaaggacgacauuagacgaaucaucuggaaagaugaaucaaagaag
guaauaauccuguagucgaaaauguugucucucuugaguggauccugagu
acgacggagcacgugaaauuccgucggaaucugggaggaccaucuccuaa
ggcuaaauacucucuagugaccgauagugaaccaguaccgugagggaaag
gugaaaagcaccccggaaggggagugaaauagaaccugaaaccgugugcu
uacaaguagucagagcccguuaaugggugauggcgugccuuuuguagaau
gaaccggcgaguuacgauuugaugcaagguuaagcaguaaauguggagcc
guagcgaaagcgagucugaauagggcguuuaguauuuggucguagacccg
aaaccaggugaucuacccuuggucagguugaaguucagguaacacugaau
ggaggaccgaaccgacuuacguugaaaagugagcggaugaacugagggua
gcggagaaauuccaaucgaaccuggagauagcugguucucuccgaaauag
cuuuagggcuagccucaagugaugauuauuggagguagagcacuguuugg
acgagcgaauucagacaaacuccgaaugccaauuaauuuaacuugggagu
cagaacaugggugauaagguccguguucgaaagggaaacagcccagacca
ccagcuaaggucccaaaauauauguuaaguggaaaaggauguggcguaca
gagugacacugcgccgaaaauguaccggggcuaaacauauuaccgaagcu
guggauuguccuuuggacaaugguaggagagcguucuaagggcguugaag
caugaucguaaggacauguggagcgcuuagaagugagaaugccgguguga
guagcgaaagacgggugagaaucccguccaccgauugacuaagguuucca
gaggaaggcucguccgcucuggguuagucggguccuaagcugaggccgac
aggcguaggcgauggauaacagguugauauuccuguaccaccuauaaucg
uaucgauggggggacgcaguaggauaggcgaagcgugcgauuggauugca
cgucuaagcaguaaggcugcgguagcugagcugugauggggagaagaccu
ucgagucguugauuucacacugccgagaaaagccucuagauagaaaauag
gugcccguaccgcaaaccgacacagguagucaagaugagaauucuaaggu
gagcgagcgaacucucguuaaggaacucggcaaaaugaccccguaacuuc
gggagaaggggugcucuuuaggguuaacgcccagaagagccgcagugaau
aggcccaagcgacuguuuaucaaaaacacaggucucugcuaaaccguaag
gugauguauaggggcugacgccugcccagugcuggaagguuaagaggagu
gguuaggcgaagcuacgaaucgaagccccaguaaacggcggccguaacua
uaacgguccuaagguagcgaaauuccuugucggguaaguuccgacccgca
cgaaaggcguaacgauuugggcacugucucaacgagagacucggugaaau
cauaguaccugugaagaugcagguuacccgcgacaggacggaaagacccc
guggagcuuuacuguagccugauauugaaauucggcuuucuaacccgcac
cacuuaucguggugggagacagugucaggcgggcaguuugacuggggcgg
ucgccuccuaaaagguaacggaggcgcucaaagguucccucagaaugguu
ggaaaucauucauagaguguaaaggcauaagggagcuugacugcgagacc
uacaagucgagcagggucgaaagacggacuuagugauccggugguuccgc
auggaagggccaucgcucaacggauaaaagcuaccccggggauaacaggc
uuaucucccccaagaguucacaucgacggggagguuuggcaccucgaugu
cggcucaucgcauccuggggcuguagucggucccaaggguugggcuguuc
gcccauuaaagcgguacgcgagcuggguucagaacgucgugagacaguuc
ggucccuauccgucgugggcguaggaaauuugagaggagcuguccuuagu
acgagaggaccgggauggacauaccucugguguaccaguugucgugccaa
cggcauagcuggguagcuauguguggacgggauaagugcugaaagcaucu
aagcaugaagccccccucaagaugagauuucccaacuucgguuauaagau
cccucaaagaugaugagguuaauagguucgagguggaagcauggugacau
guggagcugacgaauacuaaucgaucgaagacuuaau
.<<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<<......
<<<<<<.[...((.>>>.....<<<<<<<..<<<))...].>>>.....>
>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<<
<<<<<...........>>>>>>.>>.>>....<<<<<......<......
>.......>>>>.>.........<<....>>..<<<<<......<<....
.>>.....>>>>>..<<<....<<......>>.......<<<.......<
........<<<<<<<<<.<<<...<<<<<......>>>>>((......<<
<.....))>>>...>>>...>>>>>>>>.>.>..........>>>.....
.<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>>>>>..
>>>......>>.>>>>>>>.>>...............<<....>>....>
>.........<<<<....>>>>..................>>>>>>>>>>
>.......<<<<..<<<<......>>>>..>>>>...<.<........>.
>.<<<<<<....<<<<<<<.<<<<<..<<<...<<<.....>>>...>>>
...<<....>>..<<<<.....>>>>.....>>>>>.>>>>>>>..<<.<
..<<<<<<<.....<<<<<<<<<..<<<....<<<<<........>>>>>
.....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>.
..<<<.....>>>......>>>>>>...>..>.>>..<<<<<<....<<<
<<....>>>>><<<<<<<<<...<<<<<<<<<......<<...<<<<<<<
..........>>>>>>>..>>.......>>>>.>>>>>..>>>>>>>.>>
..<<<<<<<<<<......>>>>>>>>>>....<<<......>>>...<<<
<.<<<...<<<(((.....<<<<<<...........<<..<<<<.<<...
.....>>.>>>>.>>...........))).....>>>>>>.>>>...>>>
>>>><<<<<<.....>>>>>>....>>>>>><.<<<<<<<.<.......<
<<<<.<<....>>.>>>>>....>.>>>>>>>..>.....>>>>>><...
...<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<
<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<...
.>>>...>>>...>>...<<<<<........>>>>>))<<<<<<......
..<<...<<<<....<<<<...<<...<......<<<.........>>>.
..<.....<<<...<<.........>>...>>>......>..........
.........>....>>...>>>>.........>>>.>.>>.......>>>
>>>>>>>..>>.....<<......>>>>>>>.<<<<....>.>>>..>>>
>..<<<<....<<<<<<<<.<<.........<.....<<<<<........
.......>>>>><<<<<<<.<<<<....>>>>.>>>>>>>..........
..<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<....>
>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<<..<<...<<
<<<........>>>>>...>>..>>>>>>>>>..>>>>><<<<<<.....
..>>>>>>........<...........<<<<<<.....>>>>>>.....
>....>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>>>.>.....
>.....<<<<<........>>>>>..<<<<<<<<.<<<.<<......<<<
<.<<<<<<..<<<<<.<<<<<<<<<.<<<<......>>>>....<<.<<<
<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<<.....>>
>><<<<<<...........>>>>>>..<<...<<<<<<<......<<<..
.....>>>........<<.[.(((>>....>>>>>>>...<<<<..<<<.
.....>>>..>>>>.<<<....>>>.>>)))]......<<<<<<.<<<..
>>>>..>>>>>>>>>.............>>>>..>>>>>>.......<<<
<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>.......<
<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<.....
>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>
....>>..>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<....
...........>>>>>>>.<<<<<...<<<<...<<<<<<<<<<......
>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<..........
.>>>>>...>>>>.>>>>.......>>>>>>>.<<<....>>>....<<<
<<<<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>
>>...>>>..>>>>>.>>>...>>>>....>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6wqn Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		G8 K10 F21 K24 K64 K77 R78 R79 K80 N81 K83 R84 K85 G87 H88 R89 Q90 Y92
Binding residue
(residue number reindexed from 1)		G8 K10 F21 K24 K64 K77 R78 R79 K80 N81 K83 R84 K85 G87 H88 R89 Q90 Y92
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6wqn, PDBe:6wqn, PDBj:6wqn
PDBsum6wqn
PubMed32566908
UniProtQ2FXS8|RL21_STAA8 Large ribosomal subunit protein bL21 (Gene Name=rplU)

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