Structure of PDB 6wmi Chain D Binding Site BS01

Receptor Information
>6wmi Chain D (length=146) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRL
KVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGC
GRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6wmi ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression.
Resolution2.75 Å
Binding residue
(original residue number in PDB)
R228 W232 H235 Y238 R247 R265 H269 K288 N295 H299 I302 R318 F320 E322 S325 K328 H329 S349 Q350
Binding residue
(residue number reindexed from 1)
R12 W16 H19 Y22 R31 R49 H53 K72 N79 H83 I86 R102 F104 E106 S109 K112 H113 S133 Q134
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6wmi, PDBe:6wmi, PDBj:6wmi
PDBsum6wmi
PubMed33301730
UniProtQ86VK4|ZN410_HUMAN Zinc finger protein 410 (Gene Name=ZNF410)

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