Structure of PDB 6vg2 Chain D Binding Site BS01

Receptor Information
>6vg2 Chain D (length=92) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKP
NMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQ
Ligand information
Receptor-Ligand Complex Structure
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PDB6vg2 Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		R337 R340 Y343 K350 R355 Y356
Binding residue
(residue number reindexed from 1)		R59 R62 Y65 K72 R77 Y78
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:6vg2, PDBe:6vg2, PDBj:6vg2
PDBsum6vg2
PubMed33275876
UniProtQ01543|FLI1_HUMAN Friend leukemia integration 1 transcription factor (Gene Name=FLI1)

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