Structure of PDB 6uj8 Chain D Binding Site BS01
Receptor Information
>6uj8 Chain D (length=275) Species:
9606
(Homo sapiens) [
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SHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPW
IEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGC
DVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAR
EAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPS
GEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>6uj8 Chain F (length=10) Species:
9606
(Homo sapiens) [
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SPNGTIRNIL
Receptor-Ligand Complex Structure
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PDB
6uj8
Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.
Resolution
2.25 Å
Binding residue
(original residue number in PDB)
Y7 N63 Y67 Q70 E76 S77 N80 Y84 Y99 D114 Y116 Y123 T143 W147 E152 R156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 N62 Y66 Q69 E75 S76 N79 Y83 Y98 D113 Y115 Y122 T142 W146 E151 R155 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6uj8
,
PDBe:6uj8
,
PDBj:6uj8
PDBsum
6uj8
PubMed
34489470
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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