Structure of PDB 6rxm Chain D Binding Site BS01

Receptor Information
>6rxm Chain D (length=227) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPRVLVLTGAGISAESGIGLWEEHRVEDVGTPEGFDRDPELVQAFYNARR
RQLQQPEIQPNAAHLALAKLQDALGDRFLLVTQNCDNLHERAGNTNVIHM
HGELLKVRCSQSGQALDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLG
MDEIYMALSMADIFIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQV
GNEFAEKYYGPASQVVPEFVEKLLKGL
Ligand information
>6rxm Chain I (length=7) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GGAKRHR
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6rxm Evolved, Selective Erasers of Distinct Lysine Acylations.
Resolution1.92 Å
Binding residue
(original residue number in PDB)		E79 G191
Binding residue
(residue number reindexed from 1)		E33 G145
Enzymatic activity
Enzyme Commision number 2.3.1.286: protein acetyllysine N-acetyltransferase.
Gene Ontology
Molecular Function
GO:0036054 protein-malonyllysine demalonylase activity
GO:0036055 protein-succinyllysine desuccinylase activity
GO:0070403 NAD+ binding

View graph for
Molecular Function
External links
PDB RCSB:6rxm, PDBe:6rxm, PDBj:6rxm
PDBsum6rxm
PubMed32187803
UniProtP75960|NPD_ECOLI NAD-dependent protein deacylase (Gene Name=cobB)

[Back to BioLiP]