Structure of PDB 6qs8 Chain D Binding Site BS01

Receptor Information
>6qs8 Chain D (length=625) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QALKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEP
GVGKTAIVEGLAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEER
LKGVLNDLAKQEGNVILFIDALHTMVGAGMDAGNMLKPALARGELHCVGA
TTLDEYRQYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELHHHV
QITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASSIRMQIDSKPEELD
RLDRRIIQLKLEQQALMLDMLNEELSDKERQYSELEEEWKAEKLRNKVTD
AEIAEVLARWTGIPVSRMMESEREKLLRMEQELHHRVIGQNEAVDAVSNA
IRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDEAMVRID
MSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDAVEKAH
PDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELD
YAHMKELVLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLY
KRLEERGYEIHISDEALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQI
LSGELVPGKVIRLEVNEDRIVAVQH
Ligand information
>6qs8 Chain S (length=24) Species: 9913 (Bos taurus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAAAAAAAAAAAAAA
Receptor-Ligand Complex Structure
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PDB6qs8 Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Resolution3.9 Å
Binding residue
(original residue number in PDB)
K250 R252 G652 Y653 V654
Binding residue
(residue number reindexed from 1)
K92 R94 G419 Y420 V421
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
Biological Process
GO:0009408 response to heat
GO:0034605 cellular response to heat
GO:0042026 protein refolding
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6qs8, PDBe:6qs8, PDBj:6qs8
PDBsum6qs8
PubMed31216466
UniProtP63284|CLPB_ECOLI Chaperone protein ClpB (Gene Name=clpB)

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