Structure of PDB 6qic Chain D Binding Site BS01

Receptor Information
>6qic Chain D (length=629) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSIKEQRESLPVFQFRDQIIQAVKDNQILIVVGETGSGKTTQVTQYLAEA
GFTKYGMIGCTQPRRVAAVSVAKRVAEEVGCQLGQEVGYTIRFEDVTSPA
TKIKYMTDGMLQREILMDPDLKRYSVIMLDEAHERTIATDVLFALLKKTV
KRRPDLKVIVTSATLDAEKFSEYFNSCPIFTIPGRTFPVEILYSREPEPD
YLEAALTTVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKALGPSVP
ELIILPIYSALPSEMQSRIFEPAPPGSRKVVIATNIAETAITIDYIYYVV
DPGFVKQNAYDPKLGMDSLVVTPISQAQANQRAGRAGRTGPGKCFRLYTE
AAYQSEMLPTTIPDIQRQNLANTILLLKAMGINDLLRFDFMDPPPVNTML
TALEELYALGALDDEGLLTRLGRKMADFPMEPSLSKVLIASVDKGCSDEM
VTIVSMLNLQQIFYRPKDKQQQADQKKAKFHDPTGDHLTLLNVYNAWKNS
GYSNAWCFENYIQARAMRRARDVRQQIVKIMERHRHPIISCGRDTDKIRQ
ALCAGFFRNTARKDPGYKTLTEGTPVYLHPSSALFGKQAEWVLYHELVLT
TKEYMHFTTAIEPKWLVEAAPTFFKLAPT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6qic Structural basis for RNA translocation by DEAH-box ATPases.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		R611 R612 R639 T654 G656 M657 R660 G774 Q775 E776 S806 T831 N832 K853 L866 P976 R1012 Q1073 I1077 R1080 H1128 P1129 F1134 T1149 K1151 Y1153 H1155
Binding residue
(residue number reindexed from 1)		R64 R65 R92 T107 G109 M110 R113 G227 Q228 E229 S259 T284 N285 K306 L319 P429 R465 Q526 I530 R533 H579 P580 F585 T600 K602 Y604 H606
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6qic, PDBe:6qic, PDBj:6qic
PDBsum6qic
PubMed30828714
UniProtG0S700

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