Structure of PDB 6pol Chain D Binding Site BS01

Receptor Information
>6pol Chain D (length=129) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECA
AKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDE
NAICTNTVQGHSCTCKPGYVGNGTICRAE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6pol Chain D Residue 902 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6pol NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D434 I435 E437 N453 L454 L457
Binding residue
(residue number reindexed from 1)		D45 I46 E48 N64 L65 L68
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:6pol, PDBe:6pol, PDBj:6pol
PDBsum6pol
PubMed32198364
UniProtQ92832|NELL1_HUMAN Protein kinase C-binding protein NELL1 (Gene Name=NELL1)

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