Structure of PDB 6p3w Chain D Binding Site BS01

Receptor Information
>6p3w Chain D (length=256) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYK
LQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVA
EFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPAN
CKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESL
IRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNP
PETLNL
Ligand information
Receptor-Ligand Complex Structure
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PDB6p3w Structural basis for the ORC1-Cyclin A association.
Resolution2.54 Å
Binding residue
(original residue number in PDB)		M210 I213 W217 Q254 D283 T285
Binding residue
(residue number reindexed from 1)		M34 I37 W41 Q78 D107 T109
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function
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Biological Process
External links
PDB RCSB:6p3w, PDBe:6p3w, PDBj:6p3w
PDBsum6p3w
PubMed31309634
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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