Structure of PDB 6muu Chain D Binding Site BS01

Receptor Information
>6muu Chain D (length=283) Species: 342948 (Thermococcus onnurineus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDRRFYGKIVIKGKIKAVTGLHIGSQEIGGIDNPVIKDPHTGLPYIPGSS
LKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRK
INRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEE
KWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTT
HWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTG
KDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL
Ligand information
>6muu Chain G (length=25) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guggaaaggcgggcagaggcgguuu
.........................
Receptor-Ligand Complex Structure
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PDB6muu Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		I23 Q26 S54 K56 G57 R58 G129 A130 S131 N136 S139 I167 V169 R173 R181 Y224 G226 G227 S228 R231
Binding residue
(residue number reindexed from 1)		I23 Q26 S50 K52 G53 R54 G125 A126 S127 N132 S135 I163 V165 R169 R177 Y220 G222 G223 S224 R227
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6muu, PDBe:6muu, PDBj:6muu
PDBsum6muu
PubMed30503773
UniProtB6YWC0

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