Structure of PDB 6mut Chain D Binding Site BS01

Receptor Information
>6mut Chain D (length=267) Species: 342948 (Thermococcus onnurineus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDRRFYGKIVIKGKIKAVTGLHIGSQANPVIKDPHTGLPYIPGSSLKGRL
RSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGW
IHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAG
EAITEAKIEPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLLTAMALL
EDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDAREKSVS
DILSGFDSLFSEVEGKL
Ligand information
>6mut Chain G (length=20) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guggaaaggcgggcagaggc
....................
Receptor-Ligand Complex Structure
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PDB6mut Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		Q26 S53 S54 K56 G57 R58 R60 G129 A130 S131 N136 S139 E168 R181 Y224 G227 S228 R231
Binding residue
(residue number reindexed from 1)		Q26 S44 S45 K47 G48 R49 R51 G120 A121 S122 N127 S130 E159 R161 Y204 G207 S208 R211
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6mut, PDBe:6mut, PDBj:6mut
PDBsum6mut
PubMed30503773
UniProtB6YWC0

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