Structure of PDB 6mus Chain D Binding Site BS01

Receptor Information
>6mus Chain D (length=287) Species: 342948 (Thermococcus onnurineus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDRRFYGKIVIKGKIKAVTGLHIGSQRDISEIGGIANPVIKDPHTGLPYI
PGSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKF
FNRKINRGWIHVCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTK
EWEEKWRAGEAITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNV
ENTTHWRDDIKNLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDY
YRTGKDEDIVSIDAREKSVSDILSGFDSLFSEVEGKL
Ligand information
>6mus Chain G (length=33) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guggaaaggcgggcagaggcgguuugcguauug
.................................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6mus Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		I23 S53 S54 K56 G57 R58 R60 I105 G129 A130 S131 N136 S139 I167 E168 V169 I171 A178 R181 Y224 G226 G227 R231
Binding residue
(residue number reindexed from 1)		I23 S53 S54 K56 G57 R58 R60 I105 G129 A130 S131 N136 S139 I167 E168 V169 I171 A178 R181 Y224 G226 G227 R231
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6mus, PDBe:6mus, PDBj:6mus
PDBsum6mus
PubMed30503773
UniProtB6YWC0

[Back to BioLiP]