Structure of PDB 6jzw Chain D Binding Site BS01

Receptor Information

>6jzw Chain D (length=132) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168)

NANLDTLYRQVIMDHYKNPRNKGVLNDSIVVDMNNPTCGDRIRLTMKLDG
DIVEDAKFEGEGCSISMASASMMTQAIKGKDIETALSMSKIFSDMMQGKE
LGDIEALQGVSKFPARIKCATLSWKALEKGVA

Ligand information

• Ligand ID: ZN
• InChI: InChI=1S/Zn/q+2
• InChIKey: PTFCDOFLOPIGGS-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Zn++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Zn+2]
• Formula: Zn
• Name: ZINC ION
• ChEMBL: CHEMBL1236970
• DrugBank: DB14532
• PDB chain: 6jzw Chain D Residue 201

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6jzw Zinc-persulfide complex for sulfur mobilization by SufU in SUF-like machinery for Fe-S cluster biosynthesis
• Resolution: 2.64 Å
• Binding residue (original residue number in PDB): C41 D43 C66 C128
• Binding residue (residue number reindexed from 1): C38 D40 C63 C119
• Annotation score: 4

Enzymatic activity

• Enzyme Commision number: 2.-.-.-

Gene Ontology

Molecular Function

• GO:0005506 iron ion binding
• GO:0005515 protein binding
• GO:0008198 ferrous iron binding
• GO:0016740 transferase activity
• GO:0046872 metal ion binding
• GO:0051536 iron-sulfur cluster binding
• GO:0051537 2 iron, 2 sulfur cluster binding

Biological Process

• GO:0006879 intracellular iron ion homeostasis
• GO:0016226 iron-sulfur cluster assembly

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:6jzw, PDBe:6jzw, PDBj:6jzw
• PDBsum: 6jzw
• UniProt: O32163|SUFU_BACSU Zinc-dependent sulfurtransferase SufU (Gene Name=sufU)