Structure of PDB 6j8v Chain D Binding Site BS01

Receptor Information
>6j8v Chain D (length=291) Species: 67581,273057 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DDDKMLAAEAANRDHVTRCVAQTGGSPDLVAHTAALRLYLRVPHFLTEWT
TDPDRRAAVSRALALDIVSMKLLDDLMDDDTGLDRVELACVCLRLHLRAL
HELESLARDPKAVTDILEQDAVHLCGGQIRTKRSRATNLREWRAHASTYG
STFLGRYGALAAACGGEGQPADSVREFAEAFAMTITMADDLTDYDRNGER
DGNLAHLMRTGAVAGQDVVDLLEELRGRALAAVAAPPGAPGLVPVVHLYT
DDVLVRLLPRHLKKVWRVGKMISFTYRGAVSEKDAPKELLQ
Ligand information
Ligand IDFAR
InChIInChI=1S/C15H26/c1-6-14(4)10-8-12-15(5)11-7-9-13(2)3/h6,9,12H,7-8,10-11H2,1-5H3/b14-6+,15-12+
InChIKeyJXBSHSBNOVLGHF-BUJBXKITSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		CC=C(C)CCC=C(C)CCC=C(C)C
OpenEye OEToolkits 1.5.0C\C=C(/C)\CC\C=C(/C)\CCC=C(C)C
CACTVS 3.341C\C=C(C)\CC\C=C(C)\CCC=C(C)C
ACDLabs 10.04C(=C/C)(\CC/C=C(/CC/C=C(\C)C)C)C
FormulaC15 H26
NameFARNESYL
ChEMBL
DrugBank
ZINC
PDB chain6j8v Chain D Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6j8v Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism.
Resolution2.23 Å
Binding residue
(original residue number in PDB)		Q124 Y145 F149
Binding residue
(residue number reindexed from 1)		Q128 Y149 F153
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004521 RNA endonuclease activity
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:6j8v, PDBe:6j8v, PDBj:6j8v
PDBsum6j8v
PubMed30837154
UniProtA0A010;
P39476|DN7D_SACS2 DNA-binding protein 7d (Gene Name=sso7d)

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