Structure of PDB 6iqw Chain D Binding Site BS01

Receptor Information
>6iqw Chain D (length=271) Species: 523850 (Thermococcus onnurineus NA1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDRRFYGKIVIKGKIKAVTGLHIGSQPVIKDPHTGLPYIPGSSLKGRLRS
LFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIH
VCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEA
ITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIK
NLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVS
IDAREKSVSDILSGFDSLFSE
Ligand information
>6iqw Chain I (length=24) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guggaaaguggcccgaaacccuuc
........................
Receptor-Ligand Complex Structure
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PDB6iqw Cryo-EM structure of Type III-A CRISPR effector complex.
Resolution3.35 Å
Binding residue
(original residue number in PDB)		I23 G24 S53 S54 K56 G57 R58 R60 S61 G129 A130 S131 N136 I167 E168 V169 I171 Y224 G226 G227 S228 S230 R231
Binding residue
(residue number reindexed from 1)		I23 G24 S42 S43 K45 G46 R47 R49 S50 G118 A119 S120 N125 I156 E157 V158 I160 Y213 G215 G216 S217 S219 R220
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6iqw, PDBe:6iqw, PDBj:6iqw
PDBsum6iqw
PubMed30459428
UniProtB6YWC0

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