Structure of PDB 6fzv Chain D Binding Site BS01

Receptor Information
>6fzv Chain D (length=236) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVFLCGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVF
DLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMT
TDEGTGGRGFLLWYSGRAFCGGRLEKAQGTLTTPNWPESDYPPGISCSWH
IIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDA
VPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6fzv Chain D Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6fzv Structural Basis for the Acceleration of Procollagen Processing by Procollagen C-Proteinase Enhancer-1.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		E60 D68 D109 G111 T112
Binding residue
(residue number reindexed from 1)		E53 D61 D102 G104 T105
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6fzv, PDBe:6fzv, PDBj:6fzv
PDBsum6fzv
PubMed30078642
UniProtQ15113|PCOC1_HUMAN Procollagen C-endopeptidase enhancer 1 (Gene Name=PCOLCE)

[Back to BioLiP]