Structure of PDB 6f5p Chain D Binding Site BS01

Receptor Information
>6f5p Chain D (length=708) Species: 100673 (Influenza C virus (C/Johannesburg/1/66)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSKTFAEIAEAFLEPEAVRIAKEAVEEYGDHERKIIQIGIHFQVCCMFCD
EYLSTNGSDRFVLIEGRKRGTAVSLQNELCKSYDLEPLPFLCDIFDREEK
QFVEIGITRKADDSYFQSKFGKLGNSCKIFVFSYDGRLDKNCEGPMEEQK
LRIFSFLATAADFLRKENMFNEIFLPDNEETIIEMKKGKTFLELRDESVP
LPFQTYEQMKDYCEKFKGNPRELASKVSQMQSNIKLPIKHYEQNKFRQIR
LPKGPMAPYTHKFLMEEAWMFTKISDPERSRAGEILIDFFKKGNLSAIRP
KDKPLQGKYPIHYKNLWNQIKAAIADRTMVINENDHSEFLGGIGRASKKI
PEISLTQDVITTEGLKQSENKLPEPRSFPRWFNAEWMWAIKDSDLTGWVP
MAEYPPADNELEDYAEHLNKTMEGVLQGTNCAREMGKCILTVGALMTECR
LFPGKIKVVPIYARSKERKSMQEGLPVPSEMDCLFGICVKSKSHLNKDDG
MYTIITFEFSIREPNLEKHQKYTVFEAGHTTVRMKKGESVIGREVPLYLY
CRTTALSKIKNDWLSKARRCFITTMDTVETICLRESAKAEENLVEKTLNE
KQMWIGKKNGELIAQPLREALRVQLVQQFYFCIYNDSQLEGFCNEQKKIL
MALEGDKKNKSSFGFNPEGLLEKIEECLINNPMCLFMAQRLNELVIEASK
RGAKFFKT
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6f5p Chain D Residue 800 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6f5p A Mechanism for the Activation of the Influenza Virus Transcriptase.
Resolution4.14 Å
Binding residue
(original residue number in PDB)		D93 E104
Binding residue
(residue number reindexed from 1)		D93 E104
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0039694 viral RNA genome replication
GO:0075523 viral translational frameshifting
GO:0075526 cap snatching
Cellular Component
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6f5p, PDBe:6f5p, PDBj:6f5p
PDBsum6f5p
PubMed29910112
UniProtQ9IMP5|PA_INCJH Polymerase acidic protein (Gene Name=PA)

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