Structure of PDB 6f2b Chain D Binding Site BS01

Receptor Information
>6f2b Chain D (length=312) Species: 479433 (Catenulispora acidiphila DSM 44928) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PEVSAILVLTSSEASTLERVADLVTAHALYAAHDFCAQAQLAAAELPSRV
VARLQEFAWGDMNEGHLLIKGLPQVRSLPPTPTSNVHAVAATTPMSRYQA
LINECVGRMIAYEAEGHGHTFQDMVPSELELHTEQAFSPLRPDFVSLACL
RGDPRALTYLFSARQLVATLTTQEIAMLREPMWTTTVDESFLAEGRTFLL
GFERGPIPILSGADDDPFIVFDQDLMRGISAPAQELQQTVIRAYYAERVS
HCLAPGEMLLIDNRRAVHGRSIFAPRFDGADRFLSRSFIVADGSRSRHAR
SSFGRVVSARFS
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain6f2b Chain D Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6f2b Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		H178 E180 H314
Binding residue
(residue number reindexed from 1)		H132 E134 H268
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.11.-
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity

View graph for
Molecular Function
External links
PDB RCSB:6f2b, PDBe:6f2b, PDBj:6f2b
PDBsum6f2b
PubMed30410048
UniProtC7QJ42|LYS3O_CATAD L-lysine 3-hydroxylase (Gene Name=Caci_0231)

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