Structure of PDB 6cyt Chain D Binding Site BS01

Receptor Information
>6cyt Chain D (length=48) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6cyt Chain D Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6cyt Structural mechanism for HIV-1 TAR loop recognition by Tat and the super elongation complex.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		H33 C34 C37
Binding residue
(residue number reindexed from 1)		H33 C34 C37
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001070 RNA-binding transcription regulator activity
Biological Process
GO:0050434 positive regulation of viral transcription
Cellular Component
GO:0042025 host cell nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:6cyt, PDBe:6cyt, PDBj:6cyt
PDBsum6cyt
PubMed30514815
UniProtP04608|TAT_HV1H2 Protein Tat (Gene Name=tat)

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