Structure of PDB 6cqq Chain D Binding Site BS01

Receptor Information

>6cqq Chain D (length=200) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LNVEQSPQSLHVQEGDSTNFTCSFPSSNFYALHWYRWETAKSPEALFVMT
LNGDEKKKGRISATLNTKEGYSYLYIKGSQPEDSATYLCAFKAAGNKLTF
GGGTRVLVKPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDS
DVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPS

Ligand information

>6cqq Chain C (length=13) Species: 11706 (HIV-1 M:B_HXB2R) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

RFYKTLRAEQASQ

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6cqq CD4+T cell-mediated HLA class II cross-restriction in HIV controllers.
Resolution	2.8 Å
Binding residue (original residue number in PDB)	N29 F30 Y31 A105 G106 N107
Binding residue (residue number reindexed from 1)	N28 F29 Y30 A94 G95 N96

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0002250	adaptive immune response
GO:0009617	response to bacterium

	Cellular Component
GO:0005886	plasma membrane
GO:0042101	T cell receptor complex

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Biological Process

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Cellular Component

External links

PDB	RCSB:6cqq, PDBe:6cqq, PDBj:6cqq
PDBsum	6cqq
PubMed	29884618
UniProt	A0A0B4J272\|TVA24_HUMAN T cell receptor alpha variable 24 (Gene Name=TRAV24)

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