Structure of PDB 6b48 Chain D Binding Site BS01

Receptor Information
>6b48 Chain D (length=333) Species: 208963 (Pseudomonas aeruginosa UCBPP-PA14) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSVRGTISN
RLKTKDRDPAKLDASIQSPNLQTVDVANLPSDADTLKVRFTLRVLGGAGT
PSACNDAAYRDKLLQTVATYVNDQGFAELARRYAHNLANARFLWRNRVGA
EAVEVRINHIRQGEVARAWRFDALAIGLRDFKADAELDALAELIASGLSG
SGHVLLEVVAFARIGDGQEVFPSQELILDKGDKKGQKSKTLYSVRDAAAI
HSQKIGNALRTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDFY
TLLDNWVLRDEAPAVEQQHYVIANLIRGGVFGE
Ligand information
>6b48 Chain M (length=60) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cuaagaaauucacggcgggcuugauguccgcgucuaccugguucacugcc
guguaggcag
..................................................
..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6b48 Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		A13 F14 R16 V49 R50 T52 W149 R150 S228 Q229 Q258 K259 N262 E283 S290 G334
Binding residue
(residue number reindexed from 1)		A8 F9 R11 V44 R45 T47 W144 R145 S223 Q224 Q253 K254 N257 E278 S285 G329
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6b48, PDBe:6b48, PDBj:6b48
PDBsum6b48
PubMed28985564
UniProtQ02MM1|CSY3_PSEAB CRISPR-associated protein Csy3 (Gene Name=csy3)

[Back to BioLiP]