Structure of PDB 6b0r Chain D Binding Site BS01

Receptor Information
>6b0r Chain D (length=117) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRPFMCAYPGCNKRYFKLSHLQRHSRKHTGEKPYQCDFKDCERRFSRSDQ
LKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQ
KKFARSDELVRHHNMHQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6b0r Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites.
Resolution1.818 Å
Binding residue
(original residue number in PDB)		R321 Y334 K336 H339 R342 K346 R362 R366 Q369 R372 H373 R376 R390 S393 R394 H397 H401 T404 R424 E427 R430
Binding residue
(residue number reindexed from 1)		R2 Y15 K17 H20 R23 K27 R43 R47 Q50 R53 H54 R57 R71 S74 R75 H78 H82 T85 R105 E108 R111
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6b0r, PDBe:6b0r, PDBj:6b0r
PDBsum6b0r
PubMed29294058
UniProtP19544|WT1_HUMAN Wilms tumor protein (Gene Name=WT1)

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