Structure of PDB 6agb Chain D Binding Site BS01

Receptor Information
>6agb Chain D (length=227) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDRTQTFIKDCLFTKCLEDPEKPFDYQRINKNSKIALREYINNCKKNTKK
CLKLAYENKITDKEDLLHYIEEKHPTIYESLPQYVDFVPMYKELWINYIK
ELLNITKNLKTFNGSLALLKLSMADYNGALLRVTKSKNKTLIGLQGIVIW
DSQKFFIMIVKGNIIDEIKCIPKKGTVFQFEIPISDDDDSALRYSILGDR
FKYRSVDRAGRKFKSRRCDDMLYYIQN
Ligand information
>6agb Chain A (length=369) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guggaacagugguaauuccuacgauuaagaaaccuguuuacagaaggauc
cccaccuaugggcggguuaucagauauuaucaggugggaaauucggugga
acacaguggagccuuguccuccggguuaaugucgcuuuuggcauuggccc
cugcuccugagagaagaaauauacuggggaaccagucuuuaccgaccguu
guuaucagaaauucacggaguucggccuaggucggacuccgaugggaacg
gcaacgguuguuccguuugacuugucgcccgcuacggcgugagcgucaag
gucuguugagugcaaucguaggacgucauuaguggcgaacccgauaccga
uuacugcugcuguuccagc
.<<<<<<<<<<<<<..<<<<<<<........<<<<<..........<<<.
<<<.<<....>>.>>>..>>>.........>>>>>[[...{{.(((((..
......<<<<<<.........<<<<<<<<<<<<<....>>>>>>>>>>>>
...<<....>>.<<........<<<<<....>>>>>.>>....>..<<<<
<<.............<<<<<<<<<<<....>>>>>>>>>>>.........
>>>>>>...>>>>>>...<<<<<<.<<<.<<<....>>>...>>>.>>>.
>>>.............>>>>>>><<<<<....>>>>>..]]...)))))}
}...>>>>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB6agb Structural insight into precursor tRNA processing by yeast ribonuclease P.
Resolution3.48 Å
Binding residue
(original residue number in PDB)		R3 T14 E18 R80 K86 I87 K97 Y108 K189 N190 T192 L193 S204 Q205 K206 F207 K221 C222 K226 R256
Binding residue
(residue number reindexed from 1)		R3 T14 E18 R28 K34 I35 K45 Y56 K137 N138 T140 L141 S152 Q153 K154 F155 K169 C170 K174 R204
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000171 ribonuclease MRP activity
GO:0003723 RNA binding
GO:0004526 ribonuclease P activity
GO:0005515 protein binding
GO:0033204 ribonuclease P RNA binding
GO:0042134 rRNA primary transcript binding
Biological Process
GO:0000294 nuclear-transcribed mRNA catabolic process, RNase MRP-dependent
GO:0000460 maturation of 5.8S rRNA
GO:0001682 tRNA 5'-leader removal
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0008033 tRNA processing
GO:0034965 intronic box C/D snoRNA processing
Cellular Component
GO:0000172 ribonuclease MRP complex
GO:0005634 nucleus
GO:0005655 nucleolar ribonuclease P complex
GO:0030677 ribonuclease P complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6agb, PDBe:6agb, PDBj:6agb
PDBsum6agb
PubMed30262633
UniProtP38336|POP4_YEAST RNases MRP/P 32.9 kDa subunit (Gene Name=POP4)

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